Introduction: Heterocycles

Does Nature Prefer Heterocycles?

Does Nature Prefer Heterocycles?

Adventures with heterocycles.

Elucidation of mechanisms and discovery of novel reactions are interconnected, as four research chapters from the Munich laboratory demonstrate. 1) In a new opening of the furan ring, 2-methoxyfuran and tetra-acceptor-substituted ethylenes furnish methyl acrylates, which are cis-3-substituted by a cyclopropyl ring that bears the four acceptor groups. Experiments with trans- and cis-1,2-bis(trif...

Indoles and Related Heterocycles

Indole and the related heterocycles have emerged as efficient building blocks for the creation of novel anion receptors. This chapter focuses on the employment of indoles, carbazoles, and indolocarbazoles in the creation of molecular clefts, macrocycles, oligomers, and sensors. The majority of these structures utilize the heterocyclic NH as a hydrogen bond donor in binding to anions of various ...

Heterocycles from a-Aminonitriles

Owing to their various modes of reactivity, aaminonitriles represent versatile building blocks for the construction of a wide range of nitrogen heterocycles. The present Concept article focuses on synthetic methodologies using their bifunctional nature which is the basis of their reactivity as a-amino carbanions and as iminium ions. Reactions exclusively taking place on either the amine or on t...